LEVERAGING SEMICONDUCTORS FOR HIGH SENSITIVITY AND EXTREME MINIATURIZATION
AT THE CROSSROADS OF ADVANCED NANOTECH AND BIOCHEMISTRY
AT THE CROSSROADS OF ADVANCED NANOTECH AND BIOCHEMISTRY
Previous
Next

Lab-on-Skin™​ Technology

Xsensio considerably expands the potential of wearable products with the development of a breakthrough wearable device that tracks – not physical data like today’s devices – but biochemical data in the interstitial fluid (ISF). At the core of Xsensio’s wearable innovation lies our proprietary Lab-on-Skin(c) sensing chip that leverages cutting-edge nanotechnology, biochemistry and microfluidics to analyze biochemical composition directly on the body, and detect critical changes in real time that reflect physiological state.

High miniaturization will allow us to include multiple sensors on the chip, each functionalized to target a specific biomarker of interest from metabolites to ions to proteins to hormones, for a rich multiparametric analysis. Thanks to the high modularity and customization of the chip, we will leverage the same underlying technology to target a wide range of health applications. Data will be wirelessly available to the user, patient or caregiver in real time through a secured data infrastructure.

Depending on the applications targeted, the Lab-on-Skin™ chip will be configured to include a set of sensors. Xsensio envisions a unique and proprietary sensing platform of products and services that will emerge from its proprietary Lab-on-Skin(c) platform to address different applications across multiple markets. These products are all based on a common hardware platform, that consists of our wearable Lab-on-Skin(c) system that contains our core customized chip, our proprietary skin interface and a wireless communication for on-demand or continuous streaming of data. For each application, Xsensio develops, alone or with its partners, a specific data analytics tool.

Recent publications

Sheibani, S., Capua, L., Kamaei, S. et al. Extended gate field-effect-transistor for sensing cortisol stress hormone. Commun Mater 2, 10 (2021). https://doi.org/10.1038/s43246-020-00114-x

Zhang, Junrui; Rupakula, Maneesha; Bellando, Francesco; Garcia Cordero, Erick; Longo, Johan; Wildhaber, Fabien; et al. (2019): Sweat Biomarker Sensor Incorporating Picowatt, Three-Dimensional Extended Metal Gate Ion Sensitive Field Effect Transistors. ACS Publications. Collection.
https://doi.org/10.1021/acssensors.9b00597

Garcia-Cordero E, Bellando F, Zhang J, Wildhaber F, Longo J, Guérin H, Ionescu AM. Three-Dimensional Integrated Ultra-Low-Volume Passive Microfluidics with Ion-Sensitive Field-Effect Transistors for Multiparameter Wearable Sweat Analyzers.

ACS Nano. 2018 Dec 26;12(12):12646-12656. https://pubs.acs.org/doi/10.1021/acsnano.8b07413